Pathway Studio 9.0

Pathway Studio is a bioinformatics and knowledge-discovery platform developed by Ariadne Genomics, Inc. It helps researchers interpret high-throughput omics data and investigate disease mechanisms by combining a literature-derived knowledge base with interactive network visualization and analytics.

At the core of Pathway Studio is the ResNet database, populated using Ariadne’s MedScan natural language processing technology to extract and normalize biological relationships from scientific literature. Researchers can explore evidence-backed cause-and-effect links among genes, proteins, miRNAs, small molecules, diseases, and cellular processes, with direct citations to source articles.

Key capabilities include:

• Import and analysis of gene expression, RNA-seq, proteomics, and metabolomics data.
• Enrichment and causal network analyses, including Sub-Network Enrichment Analysis (SNEA) and upstream regulator identification.
• Interactive pathway and network building, editing, and annotation, with flexible visualization and filtering.
• Literature traceability for every relationship, supporting transparent, evidence-driven conclusions.
• Cross-species support (e.g., human, mouse, rat) and integration with common identifiers and ontologies.
• Options for desktop and server/web deployment to fit individual or enterprise workflows.

Common use cases span hypothesis generation, mechanism-of-action studies, target and biomarker discovery, and drug repurposing. By unifying curated knowledge with powerful analytics, Pathway Studio enables researchers to move from raw data to interpretable biological insights efficiently and reproducibly.

Pathway Studio is developed by Ariadne Genomics, Inc.. The most popular versions of this product among our users are: 5.0, 7.0, 7.1 and 9.0. The name of the program executable file is PWDoc.exe.